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患者男性,22岁,于1963年9月1日入院。患者于1963年8月28日发高烧,腹泻每日20余次,里急后重,大便伴有脓血。入院时体温39.4℃,脉搏92次/分,四肢关节无异常。大便镜检:红细胞(++),白细胞(+++),吞噬糊胞(++),诊断为细菌性痢疾。用合霉素治疗5天后,症状消失,大便正常。9月7日患者又发热39.0℃,左膝关节及双足踝关节肿痛,左腿呈屈曲状,有明显压痛,但无波动。血红细胞480万,白细胞7,400,中性69%,淋巴27%,嗜酸2%,单核2%,血沉109毫米/第一小时末,血小板38万,出凝血时间各一分半钟。曾应用阿斯匹林、泼尼松、甘草粉、保泰松等治疗,症状不仅无改善反而加重,患者大量出汗,手指腰骶及两膝关节肿痛严重,膝关
The patient, male, 22 years old, was admitted on September 1, 1963. Patients in August 28, 1963 high fever, diarrhea more than 20 times daily, tenesmus, stool with pus and blood. Body temperature at admission 39.4 ℃, pulse 92 beats / min, limbs and joints without exception. Stool microscopy: red blood cells (++), white blood cells (+++), phagocytosis (++), diagnosis of bacterial dysentery. After 5 days of treatment with coxomycin, the symptoms disappeared and the stool was normal. On September 7, the patient developed fever of 39.0 ° C. His left knee and foot had ankle swelling and swelling. His left leg was buckled and showed tender tenderness but no fluctuations. 4.8 million red blood cells, white blood cells 7,400, 69% neutral, 27% lymphatic, eosinophilic 2%, mononuclear 2%, erythrocyte sedimentation rate 109 mm / first hour, platelets 380 000, a clotting time of one and a half minutes. Has used aspirin, prednisone, licorice powder, phenylbutazone and other treatment, the symptoms not only improved but worse, a large number of patients sweating, finger lumbosacral and two knee joint swelling and pain, knee