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人体血清醛缩酶(ALD)有A、B、C三种同功酶,这些酶有器官特异性,ALD_(-A)主要分布在骨骼肌中,ALD_(-B)存于肝内,而ALD_(-C)则主要分布在脑与神经组织中。作者用放射免疫法(RIA)对脑血管疾病患者进行了血清ALD_(-A)及ALD_(-C)测定,并设立了健康对照组。健康人12名,其血清ALD_(-C)值正常上限为4ng/ml;ALD_(-A)之正常上限为210ng/ml。脑血管意外患者18例,其中脑梗塞5例,脑出血13例,均经CT扫描证实,部分病人经开颅手术确诊。所有病例均于入院后立即测定血清ALD_(-A)与ALD_(-C),并对部分病人两种酶之动态变化进行了观察。脑梗塞5例,除死亡1例外,余血清ALD_(-A)、
Human serum aldolase (ALD) has three isozymes A, B and C. These enzymes have organ specificity. ALD_ (- A) is mainly distributed in skeletal muscle and ALD_ (- B) ALD _ (- C) is mainly distributed in brain and nerve tissue. The authors used radioimmunoassay (RIA) to detect serum ALD_ (- A) and ALD _ (- C) in patients with cerebrovascular disease and established a healthy control group. 12 healthy people, the serum ALD _ (- C) normal upper limit of 4ng / ml; ALD _ (- A) of the normal upper limit of 210ng / ml. 18 cases of cerebrovascular accident patients, including cerebral infarction in 5 cases, 13 cases of cerebral hemorrhage, confirmed by CT scanning, some patients diagnosed by craniotomy. All cases were measured serum ALD _ (- A) and ALD _ (- C) immediately after admission, and the dynamic changes of two enzymes in some patients were observed. 5 cases of cerebral infarction, except one died, the remaining serum ALD _ (- A),