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P物质(substance P,SP)是一种神经肽类物质,与肥大细胞相关,含神经肽的神经可发挥神经系统对宿主防御反应的调节机制作用。本文作者报告了颞下颌关节(TMJ)中SP和肥大细胞鉴定的研究。 病例和方法 本组9例TMJ功能失常病例均为女性,平均年龄38岁(32～40岁),单侧TMJ功能失常4例(44％),双侧5例(56％)。所有病例为关节盘脱位,大多数伴发不同程度TMJ退行性变,8例先前经聚合酶链反应(PCR)测定,在后双板组织
Substance P (SP) is a neuropeptide that is associated with mast cells. Neuropeptide-containing nerves exert the regulatory mechanisms by which the nervous system responds to host defense. The authors report the identification of SP and mast cells in the temporomandibular joint (TMJ). Cases and Methods All 9 patients with TMJ dysfunction were female. The average age was 38 years old (32-40 years). Unilateral TMJ dysfunction was found in 4 cases (44%) and bilateral (5 cases) in 56 cases. All cases were dislocation of the articular disc, most of them with varying degrees of TMJ degeneration, 8 cases were previously detected by polymerase chain reaction (PCR)