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目的分析本院小儿心脏手术围术期预防用抗菌药物合理情况。方法抽取常州市儿童医院2015年小儿心脏手术归档病例50例,对其抗菌药物的品种选择、给药时间、用法用量、用药疗程、更换药物等项目进行统计分析。结果 50例病例中,抗菌药物使用率为100%,其中合理者14例(28%)。不合理用药主要包括疗程过长、无指征更换药物、用法用量不正确等;预防用抗菌药物主要为第2代头孢菌素,其次为头霉素类。结论本院2015年小儿心脏手术围术期预防用药基本合理,但仍存在抗菌药物使用时间过长、无指征更换药物等问题,有待进一步规范。
Objective To analyze the reasonable situation of perioperative prophylactic antibiotics in pediatric cardiac surgery. Methods Fifty cases of pediatric cardiac surgery filial cases were collected from Children’s Hospital of Changzhou in 2015, and their antibacterial drug selection, dosing time, dosage, medication course and drug replacement were analyzed statistically. Results Among the 50 cases, the antibacterial usage was 100%, of which 14 were reasonable (28%). Irrational use of drugs, including treatment is too long, no indication of the replacement of drugs, usage and dosage is not correct; preventive antibacterial drugs are mainly the second generation cephalosporins, followed by the class of cephamycins. Conclusion The perioperative prophylaxis of pediatric cardiac surgery in our hospital was basically reasonable in 2015, but there are still some problems such as prolonged use of antibacterial drugs and no indication of drug replacement, which needs further specification.