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[目的]制备以改性的β-环糊精为载体的七氟菊酯微胶囊。[方法]以聚乙烯醇-1788为乳化分散剂,运用溶剂挥发法制备微胶囊,使用激光粒度分析仪、光学显微镜、扫描电镜对微胶囊进行形貌表征,用紫外分光光度计研究微胶囊的缓释行为。[结果]β-环糊精与PBS按4∶3的比例共混改性后制备的载体微胶囊的包封率为87.08%、载药量为57.81%,平均粒径为10μm,缓释期为25~27 d。[结论]改性后的β-环糊精载体微胶囊具有较好的结构形貌,载药量和包封率均比脲醛树脂载体微胶囊高,且缓释性更好。
[Objective] To prepare tefluthrin microcapsules with modified β-cyclodextrin as carrier. [Method] The microcapsules were prepared by solvent evaporation method with polyvinyl alcohol-1788 as emulsifying and dispersing agent. The morphology of the microcapsules was characterized by laser particle size analyzer, optical microscope and scanning electron microscope. The microcapsules were characterized by UV spectrophotometer Slow release behavior. [Result] The entrapment efficiency of the carrier microcapsules prepared by blending β-cyclodextrin and PBS at a ratio of 4: 3 was 87.08%, the drug loading was 57.81%, the average particle size was 10 μm, and the sustained release period For 25 ~ 27 d. [Conclusion] The modified β-cyclodextrin microcapsules have better structure morphology, drug loading and entrapment efficiency than urea-formaldehyde resin carrier microcapsules, and better sustained-release properties.