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目的:探讨格列美脲联合二甲双胍治疗2型糖尿病患者的临床价值。方法:选取我院在2011年1月至2013年1月收治的2型糖尿病患者58例,将所有患者随机平分为观察组和对照组,观察组联合应用格列美脲和二甲双胍治疗,对照组仅给予格列美脲治疗,并对两组治疗效果进行比较。结果:治疗2个疗程后观察组FBG、2hBG和HbA1c三项指标的变化情况均明显优于对照组,总有效率明显大于对照组,且P<0.05。结论:格列美脲联合二甲双胍治疗2型糖尿病患者安全、有效,值得临床推广。
Objective: To investigate the clinical value of glimepiride combined with metformin in the treatment of type 2 diabetes mellitus. Methods: Fifty-eight patients with type 2 diabetes treated in our hospital from January 2011 to January 2013 were randomly divided into observation group and control group. The observation group was treated with glimepiride and metformin, while the control group Only glimepiride treatment, and the treatment effect of the two groups were compared. Results: After 2 courses of treatment, the changes of FBG, 2hBG and HbA1c in the observation group were significantly better than those in the control group, and the total effective rate was significantly greater than that in the control group (P <0.05). Conclusion: Glimepiride and metformin are safe and effective for type 2 diabetes mellitus, which is worthy of clinical promotion.