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目的:探讨脂肪肝的血液流变学及血脂异常特征及临床意义。方法:检测脂肪肝患者52例和正常对照43例,空腹抽静脉血,肝素抗凝,测定全血比黏度、血浆比黏度、血沉、血沉K值、压积和纤维蛋白原及甘油三酯、胆固醇等指标,计算红细胞聚集指数。结果:脂肪肝患者的全血比黏度、血浆比黏度、压积、红细胞聚集指数和纤维蛋白原及血脂指标较正常对照组显著升高(P<0.01和0.001)。血沉和血沉K值较正常对照组低(分别为P<0.01和0.02)。结论:脂肪肝患者血液流变性及血脂明显异常,高血脂及血液黏度增加促使脂肪肝的形成。
Objective: To investigate the hemorheology and dyslipidemia of fatty liver and its clinical significance. Methods: Fifty-two patients with fatty liver and 43 normal controls were studied. Fasting venous blood and heparin anticoagulation were performed. The whole blood viscosity, plasma specific viscosity, erythrocyte sedimentation rate, erythrocytosis, erythrocyte sedimentation rate, erythrocyte sedimentation rate, erythrocyte sedimentation rate, triglyceride, Cholesterol and other indicators, calculate the erythrocyte aggregation index. Results: The whole blood viscosity, plasma specific viscosity, hematocrit, erythrocyte aggregation index, fibrinogen and lipids in patients with fatty liver were significantly higher than those in normal controls (P <0.01 and 0.001). Erythrocyte sedimentation rate and erythrocyte sedimentation rate K values ?? lower than the normal control group (P <0.01 and 0.02, respectively). Conclusion: The patients with fatty liver have abnormal blood rheology and blood lipids, and hyperlipemia and blood viscosity increase the formation of fatty liver.