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作者对273例初治急性髓细胞白血病(AML)用ADOAP 方案(阿霉素、长春新碱、阿糖胞苷和强的松)作诱导缓解。另105例≥50岁初治者取 ROAP方案(R 为苯甲酰腙柔红霉素),总共378例。预防性措施包括:板层气流净化室及抗菌素;血小板低于2万者输血小板;白细胞>5万者作白细胞去除术。378例中161例(43％)未达到完全缓解(CR)。
The authors induced remission in 273 newly diagnosed acute myeloid leukemias (AML) using the ADOAP regimen (doxorubicin, vincristine, cytarabine and prednisone). The other 105 patients ≥50 years old who took ROAP regimen (R is benzoyl hydrazone daunorubicin), a total of 378 cases. Preventive measures include: lamellar airflow purification room and antibiotics; platelets less than 2 million platelet transfusions; white blood cells> 50,000 people for leukapheresis. Of the 378 cases, 161 (43%) did not achieve complete remission (CR).