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目的：探讨谷胱甘肽对病毒性肝炎病人ＳＯＤ和ＬＰＯ的影响及疗效。方法：治疗组２６例，男性２０例，女性６例；年龄３６±ｓ１０ａ。用肌苷０．４ｇ，甘草酸单铵６０ｍＬ或甘草酸二铵３０ｍＬ和门冬氨酸钾镁２０ｍＬ均加入１０％葡萄糖注射液２５０ｍＬ中静脉滴注（静滴），ｑｄ作基础治疗，同时用谷胱甘肽１．２ｇ，静滴，ｑｄ；对照组２５例，男性１８例，女性７例；年龄３２±９ａ，仅给予基础治疗。结果：治疗组ＴＢ，ＤＢ，ＡＬＴ分别下降３９±４６μｍｏｌ／Ｌ，１８±３２μｍｏｌ／Ｌ，７６±１１３ＩＵ／Ｌ，均优于对照组（分别为２９±４２μｍｏｌ／Ｌ，１４±３０μｍｏｌ／Ｌ，３９±１００ＩＵ／Ｌ），Ｐ值分别＜０．０１，０．０５和０．０１，但治疗前后ＳＯＤ（分别为４０±１０Ｕ／ｍＬ，４２±１５Ｕ／ｍＬ），ＬＰＯ（分别为０．５±０．５μｍｏｌ／Ｌ，０．４±０．３μｍｏｌ／Ｌ）无明显变化（Ｐ＞０．０５）。结论：谷胱甘肽对肝功能恢复有良好疗效，但不影响ＳＯＤ和ＬＰＯ水平
Objective: To investigate the effect and effect of glutathione on SOD and LPO in patients with viral hepatitis. Methods: The treatment group of 26 cases, 20 males and 6 females; age 36 ± s10a. With inosine 0.4g, glycyrrhizic acid 60mL or glycyrrhizic acid 30mL and potassium aspartate 20mL are added 10% glucose injection 250mL intravenous infusion (intravenous infusion), qd for basic treatment, at the same time with Glutathione 1.2g, intravenous infusion, qd; control group of 25 patients, 18 males and 7 females; aged 32 ± 9a, only given basic treatment. Results: The levels of TB, DB and ALT in treatment group decreased by 39 ± 46μmol / L, 18 ± 32μmol / L and 76 ± 113IU / L respectively, which were significantly higher than those in control group (29 ± 42μmol / L, 14 ± 30μmol / L, 39 ± 100 IU / L), P values were <0.01, 0.05 and 0.01, respectively, but before and after treatment, SOD was 40 ± 10U / mL and 42 ± 15U / mL, LPO was 0.5 ± 0.5μmol / L, 0.4 ± 0.3μmol / L) had no significant change (P> 0.05). Conclusion: Glutathione has a good effect on the recovery of liver function, but does not affect the level of SOD and LPO