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目的探讨类似卵巢性索肿瘤的子宫肿瘤的病理特点及生物学行为。方法收集临床资料、观察HE切片、行免疫组化检测,对病例进行诊断与鉴别诊断。结果 2例临床上分别表现为子宫内膜息肉及腺肌瘤。例1于息肉内见多样的形态改变,且细胞核级别高,部分细胞黄素化,免疫组化CD10、inhibin均(+);例2组织形态单一,于平滑肌束间见肿瘤细胞条索分布,细胞温和,可见核膜折叠或核沟,免疫组化CD10(-),inhibin散在弱(+)。结论类似卵巢性索肿瘤的子宫肿瘤诊断需注意结合形态及免疫组化标记,其分化与成熟度可能具有预后提示作用。
Objective To investigate the pathological features and biological behavior of ovarian tumors resembling ovarian tumors. Methods Clinical data were collected, HE sections were observed and immunohistochemistry was performed to diagnose and differentiate the cases. Results 2 cases of clinical manifestations of endometrial polyps and adenomyosis. Example 1 In the polyp see a variety of morphological changes, and the high level of nuclei, some of the cells luteinized, immunohistochemical CD10, inhibin were (+); Example 2 single tissue morphology in the smooth muscle bundle see the tumor cell cord distribution, mild cell , Visible nuclear membrane fold or nuclear ditch, immunohistochemical CD10 (-), inhibin scattered weak (+). Conclusions Uterine tumors resembling ovarian tumors should be noticed by the combination of morphological and immunohistochemical markers. The differentiation and maturation may have prognostic implications.