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前体脂质体(Proliposome,PL)是指脂质体的组份和赋形剂的脱水形式,它加水后能重建成脂质体,解决了脂质体以溶液形式储存的稳定性问题。肝素作为抗凝药物在临床上具有重要的价值,但注射给药方式给应用带来了不便。低分子量肝素(LMWH)口服剂型的开发是人们研究的热点,有
Proliposomes (PL) refer to the dehydrated forms of liposome components and excipients that, when added to water, reconstitute into liposomes, solving the stability problem of liposomes being stored in solution. Heparin is clinically valuable as an anticoagulant drug, but it has been inconvenient to administer it by injection. The development of low molecular weight heparin (LMWH) oral dosage forms is a hot research topic