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目的探讨大剂量尿激酶脑室内灌注,溶解脑室血肿的治疗效果。方法2000年4月～2003年5月,我们对38例原发性高血压脑室出血的病人进行脑室、腰大池置管,建立外引流通道,大剂量尿激酶脑室内灌注治疗。结果术后1-4d脑室内血肿完全引出,缩短了血肿吸收期。术后3-24h神志清醒达61%。出院时GOS评分:优良9例,轻残15例,重残7例,植物生存3例,死亡4例。结论脑室、腰大池置管全脑室系统冲洗引流、大剂量尿激酶脑室内灌注治疗脑室血肿,效果满意。
Objective To investigate the therapeutic effect of high-dose urokinase intraventricular perfusion and dissolution of ventricular hematoma. Methods From April 2000 to May 2003, 38 patients with essential hypertensive ventricular hemorrhage were catheterized in the ventricles and lumbar labyrinths, and the external drainage channel was established. Intravenous perfusion of high-dose urokinase was performed. Results Intraventricular hematoma was completely induced 1-4 days after operation, which shortened the period of hematoma absorption. Postoperative 3-24h consciousness up to 61%. At discharge, the GOS score was excellent in 9 cases, mild disability in 15 cases, severe disability in 7 cases, plant survival in 3 cases and death in 4 cases. Conclusions The ventricular and lumbar cistern was cannulated by flushing and draining of the whole ventricular system, intraventricular perfusion with high dose of urokinase was effective in treating ventricular hematoma.