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文献记载,磺胺剂应用后能发生发热、头晕、急性溶血性贫血、皮疹、发绀、颗粒性白血球减少等毒性反应。关于引起癲癎样反应尚未见过报告。1957年我院遇到一例磺胺噻唑引起发热、颗粒性白血球减少、并伴有癫癎样发作。今报导于后供同道参考。病例报告:患者米××,住院号0880,男性,21岁。于1957年9月3日因腹痛排脓血便而入院。患者自诉于一日前开始腹痛,初排水样便三次后,便脓血便,一日十多次。里急后重,发冷发烧,头痛头晕,全身乏力,食欲不振,后经门诊给予白色药片每四小时一次,每次四片,服后未见效,即在翌日送来我院。既往症和家族史:个人平时健康,少许吸烟,不饮酒否认冶游及性病史,喜欢运动。家属及个人否认精神神经病史。父母均健在。体检:脉搏96/分,体温39.2℃。血压120/78毫米汞柱,发育正常,营养良好。神智清楚,合作自
Literature records, sulfonamides can occur after the application of fever, dizziness, acute hemolytic anemia, rash, cyanosis, granulocytopenia and other toxic reactions. There have not been any reports about causing epileptiform responses. In 1957, our hospital encountered a case of sulfathiazole caused fever, granulocytic leukopenia, and accompanied by epileptic seizures. This report is for reference later in the story. Case report: patient × ×, hospital number 0880, male, 21 years old. September 3, 1957 due to abdominal pain row pus and admission. Patient self-prosecution started in a day before abdominal pain, the first drainage of urine will be three times, then pus and blood will be more than a dozen times a day. Tenesmus, fever, headache, dizziness, malaise, loss of appetite, after the clinic to give white pills once every four hours, each four, after serving no effect, that is, the next day sent to our hospital. Past illness and family history: Individuals usually healthy, a little smoking, no drinking denied the rule of law and sex history, like exercise. Family members and individuals deny psychiatric history. Parents are alive. Physical examination: pulse 96 / min, body temperature 39.2 ℃. Blood pressure 120/78 mm Hg, normal development, good nutrition. Clear-minded, co-operation since