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目的探讨中西医结合一体化治疗阿拉伯国家慢性肾脏病患者的临床疗效。方法选取2012年12月至2015年12月在我院住院治疗的阿拉伯国家慢性肾脏病患者378例,按照随机数表法分为对照组和观察组,每组189例。对照组患者采用西医对症与辨证口服中药治疗,观察组采用西医对症与辨证口服中药治疗的基础上,加用口服脉康合剂与双肾区外敷、熏蒸、药浴、灸疗等一系列中医外治方法,治疗6个月。比较两组患者的临床症状积分、肾功能相关指标、生存质量和临床疗效。结果观察组患者的倦怠乏力、腰酸腿软、食少纳呆、畏寒肢冷、水肿[(1.56±0.32)分、(1.87±0.83)分、(1.72±0.74)分、(1.21±0.73)分、(1.34±0.93)分]等临床症状积分明显低于对照组的(2.13±0.72)分、(2.52±0.81)分、(2.37±0.69)分、(1.89±0.78)分、(3.05±0.98)分,差异均有统计学意义(P<0.05);观察组患者的24 h尿蛋白定量[(0.81±0.62)g/m L]、尿素氮[(8.16±1.87)mmol/L]和尿酸[(403.29±81.25)μmol/L]明显低于对照组的(1.24±0.72)g/m L、(9.57±2.14)mmol/L、(452.19±83.74)μmol/L,肾小球滤过率[(56.71±13.65)m L/(min·1.73 m2)]明显高于对照组的(49.37±10.21)m L/(min·1.73 m2),差异均有统计学意义(P<0.05);观察组患者的情绪功能、认知功能、角色功能、躯体功能和社会功能评分[(69.37±11.04)分、(70.83±12.27)分、(74.11±11.83)分、(75.21±11.33)分、(78.77±12.29)分]高于对照组的(63.26±11.23)分、(65.63±12.17)分、(67.56±11.57)分、(68.69±11.56)分、(72.17±13.52)分,差异均有统计学意义(P<0.05);观察组的治疗总有效率为80.95%,明显高于对照组的67.72%,差异有统计学意义(P<0.05)。结论中西医结合一体化治疗阿拉伯国家慢性肾脏病可改善患者的临床症状、改善肾功能,提高生活质量,具有较好的临床疗效。
Objective To explore the clinical efficacy of integrated traditional Chinese and western medicine in the treatment of chronic kidney disease in Arab countries. Methods 378 cases of chronic kidney disease in Arab countries hospitalized in our hospital from December 2012 to December 2015 were divided into control group and observation group according to the random number table method, with 189 cases in each group. The patients in the control group were treated with western medicine symptomatic and dialectical oral Chinese medicine, and the observation group were treated with western medicine symptomatic and dialectical oral traditional Chinese medicine. The patients in the control group were treated with oral Maikang mixture and external application of double kidney area, fumigation, medicated bath and moxibustion Treatment method, treatment for 6 months. Clinical symptom score, renal function related indicators, quality of life and clinical efficacy were compared between the two groups. Results The patients in the observation group had fatigue, backache and leg weakness, poor appetite, aversion to cold and edema (1.56 ± 0.32, 1.87 ± 0.83, 1.72 ± 0.74, 1.21 ± 0.73, (1.34 ± 0.93) points and other clinical symptom scores were significantly lower than those in the control group (2.13 ± 0.72), (2.52 ± 0.81) points, (2.37 ± 0.69) points, (1.89 ± 0.78) points and (3.05 ± (0.81 ± 0.62) g / m L], urea nitrogen [(8.16 ± 1.87) mmol / L], and the difference was statistically significant (P 0. 05) Uric acid [(403.29 ± 81.25) μmol / L] was significantly lower than that of the control group (1.24 ± 0.72 g / m L, 9.57 ± 2.14 mmol / L, 452.19 ± 83.74 μmol / L, (56.71 ± 13.65) m L / (min · 1.73 m2)] was significantly higher than that of the control group (49.37 ± 10.21) m L / (min · 1.73 m2), respectively, with statistical significance (P <0.05) (69.37 ± 11.04), (70.83 ± 12.27) points, (74.11 ± 11.83) points and (75.21 ± 11.33) points respectively in the observation group were significantly higher than those in the control group (P0.05). The scores of emotional function, cognitive function, role function, physical function and social function in observation group were 78.77 ± 12.29) was higher than that of the control group (63.26 ± 11.23), (65.63 ± 12.17), (67.56 ± 11.57), (68.69 ± 11.56), (72.1 7 ± 13.52), the differences were statistically significant (P <0.05). The total effective rate of the observation group was 80.95%, which was significantly higher than that of the control group (67.72%), the difference was statistically significant (P <0.05). Conclusion Integrated Chinese and Western medicine treatment of chronic kidney disease in Arab countries can improve clinical symptoms, improve renal function, improve quality of life, with good clinical efficacy.