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慢性淋巴细胞白血病(CLL)是一种异质性疾患。约95%的患者为B淋巴细胞单克隆增殖,少数患者为T淋巴细胞受累。多发生于50岁以上的老年人,偶见于青年或儿童。男性多于女性。中位生存期5年左右,部分患者在诊断后1年内死亡,而一些患者则生存10年以上。因此,对CLL患者预后因素的鉴别,对预测患者病情的发展、确定治疗方案或观察疗效以及监视疾病是否恶化均有十分重要的意义。近年来,在预测患者预后方面有了重要进展,一些学者
Chronic lymphocytic leukemia (CLL) is a heterogeneous disorder. About 95% of patients are monoclonal B cell proliferation, a small number of patients with T lymphocyte involvement. Occur in the elderly over the age of 50, occasionally young or children. More men than women. The median survival is about 5 years, some patients died within 1 year after diagnosis, while some patients survived for more than 10 years. Therefore, the identification of prognostic factors in patients with CLL, the prognosis of patients with the development of the disease, determine the treatment program or observe the efficacy and monitoring of disease are of great significance. In recent years, significant progress has been made in predicting patient outcomes, some scholars