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目的探讨手术切除加术中温水浴疗治疗肝癌的安全性及临床应用的意义。方法回顾我院2010年6月至2013年6月手术切除治疗肝癌73例,随机分成两组,A组37例(研究组)采取手术切除加术中温水浴疗治疗,B组(对照组)36例采取单纯手术切除治疗。比较两组的手术前后免疫功能变化、术后并发症、死亡率、恢复时间、复发率、生存率以及治疗费用等指标差异。结果两组在术后并发症、死亡率、术后恢复时间及治疗费用方面相似,差异无统计学意义(P>0.05),但在免疫功能变化方面两组差异显著,具有统计学意义(P<0.05),研究组术后复发率较对照组低,而生存率较对照组高,两者间差异具有统计学意义(P<0.05)。结论手术切除加术中温水浴疗是一种安全、有效的肝癌综合治疗方法,其具有操作简单、价格便宜、微创或无创的特点,值得推广应用。
Objective To investigate the safety and clinical significance of surgical resection plus warm water bath in the treatment of liver cancer. Methods From June 2010 to June 2013, 73 cases of hepatocellular carcinoma treated by surgical resection were randomly divided into two groups. Group A (37 cases) Thirty-six patients underwent simple surgical resection. The changes of immune function, postoperative complications, mortality, recovery time, relapse rate, survival rate and treatment cost were compared between the two groups before and after surgery. Results There were no significant differences in postoperative complications, mortality, postoperative recovery time and treatment costs between the two groups (P> 0.05), but there were significant differences between the two groups in the changes of immune function (P <0.05). The recurrence rate of the study group was lower than that of the control group and the survival rate was higher than that of the control group. The difference between the two groups was statistically significant (P <0.05). Conclusions Surgical resection plus intraoperative warm water bath is a safe and effective method for comprehensive treatment of liver cancer. It has the characteristics of simple operation, cheap price, minimally invasive or noninvasive, which is worth popularizing and applying.