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凝血第Ⅷ因子(FⅧ)的促凝活性依赖于其分子中重链与轻链的裂解,继而形成激活的FⅧ。其中,FⅧ轻链在1689位精氨酸处被凝血酶裂解;生成72kd片断。本文采用简单而灵敏的方法免疫纯化和
The procoagulant activity of coagulation factor VIII (FⅧ) relies on the cleavage of the heavy and light chains in its molecule, which in turn leads to the formation of activated FⅧ. Among them, the F VIII light chain at arginine 1689 was thrombin cleavage; generate 72kd fragment. This article uses a simple and sensitive method to immunopurify and