Ubiquitous expression of Sry induces embryonic lethality related to suppression of Tie2/Tek expressi

• 作 者: Kazuhisa Yoshida Masanori Ito
• 机 构: 不详
• 出 处: 生命科学与技术进展(英文)
• 发表日期: 2010年5期
• 关键词: SRY Tie2/Tek TRANSGENIC Mice SryTie2/TekTransgenic Mice

Sry (sex-determining region on the Y chromosome) is a mammalian sex-determining gene on the Y chromosome. In mice, the transient expression of Sry in supporting cell precursor cells between 10.5 and 12.5 days post-coitus (dpc) triggers the differentiation