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目的探讨鼻胆管引流预防ERCP术后急性胰腺炎和高淀粉酶血症的疗效。方法对泰州市人民医院行治疗性ERCP患者110例随机分成引流组和对照组,观察两组术后2 h和术后24 h血淀粉酶值,比较高淀粉酶血症和术后急性胰腺炎发生率。结果引流组术后2 h、术后24 h血淀粉酶值明显低于对照组(P<0.01),引流组术后高淀粉酶血症明显低于对照组(P<0.05),引流组无急性胰腺炎,常规治疗组有6例胰腺炎。结论鼻胆管引流能有效预防ERCP术后急性胰腺炎和高淀粉酶血症。
Objective To investigate the curative effect of nasobiliary drainage on the prevention of acute pancreatitis and hyper amylasemia after ERCP. Methods One hundred and ten cases of therapeutic ERCP in Taizhou People’s Hospital were randomly divided into drainage group and control group. The blood amylase values at 2 h and 24 h after operation were compared between the two groups. The patients with high amylase and acute pancreatitis Occurrence rate. Results The value of serum amylase at 2 h postoperatively and at 24 h postoperatively was significantly lower in the drainage group than in the control group (P <0.01). The hypermylase activity in the drainage group was significantly lower than that in the control group (P <0.05) Acute pancreatitis, conventional treatment group had 6 cases of pancreatitis. Conclusion Nasobiliary drainage can effectively prevent acute pancreatitis and hyper amylasemia after ERCP.