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已经证明人类乳头状瘤病毒(HPV)与泌尿生殖道某些癌前病变及恶性肿瘤相关,尤其是宫颈癌。近年虽多数学者的工作证实HPV与膀胱移行细胞癌(TCC)有关,但尚存争议。本文用多聚酶链反应(PCR),对18例新鲜膀胱TCC标本进行HPV分析,结果3例(167%)膀胱肿瘤HPV阳性,据此认为HPV与膀胱TCC有关。
Human papillomavirus (HPV) has been shown to be associated with certain precancerous and malignant tumors of the genitourinary tract, especially cervical cancer. Although most scholars work in recent years confirmed that HPV and bladder transitional cell carcinoma (TCC), but still controversial. In this paper, 18 cases of fresh bladder TCC specimens were analyzed by polymerase chain reaction (PCR), and results of 3 cases (16.7%) of bladder cancer HPV-positive, HPV and bladder TCC.