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目的:探讨胃肠道间质瘤的诊断和治疗方法。方法:对1998~2005年收治的32例胃肠道间质瘤病人的临床表现、手术处理及病理结果进行回顾分析。结果:肿瘤多位于胃部,最多的临床表现为腹部隐痛不适。手术前81.3%(26/ 32)的病例有不同程度的误诊。均行外科手术切除。其中因复发而行2次手术者10例。3次手术者8例。随访时间6个月~5年,死亡8例。结论:胃肠道间质瘤缺乏特异性临床表现,术前确诊率较低,其确诊依靠病理结果。目前胃肠道间质瘤的治疗仍以手术切除为主,对复发或远处转移者积极再次手术可延长生存期。
Objective: To investigate the diagnosis and treatment of gastrointestinal stromal tumors. Methods: The clinical manifestations, surgical treatment and pathological findings of 32 patients with gastrointestinal stromal tumors admitted from 1998 to 2005 were retrospectively analyzed. Results: Most tumors located in the stomach, the most clinical manifestations of abdominal pain and discomfort. 81.3% (26/32) cases had misdiagnosis before operation. All underwent surgical resection. Among them, 10 cases were operated twice because of recurrence. 3 times in 8 cases. Follow-up time of 6 months to 5 years, 8 patients died. Conclusion: Gastrointestinal stromal tumors lack of specific clinical manifestations, the preoperative diagnosis rate is low, the diagnosis depends on the pathological results. The current treatment of gastrointestinal stromal tumors are still mainly surgical resection of the recurrence or distant metastasis of positive re-surgery can extend the survival.