A Novel Frequent BRCA1 Allele in Chinese Patients with Breast Cancer

• 作 者: 周冬仙 熊文 徐红先 邵超鹏
• 机 构: DepartmentofBreastandThyroidGlandSurgery,TheSecondHospitalofJinanUniversityMedicalCollege,ShenzhenBl
• 出 处: 华中科技大学学报(医学英德文版)
• 发表日期: 2006年5期
• 关键词: 等位基因 乳腺癌 病理 治疗 BRCA1 sequencing single nucleotide polymorphism PCR-SSP Chine

<正>The whole length of exon 11 of BRCA1 was sequenced (total 3427 bp) in 59 patients and 10 healthy female blood donors. To allow a rapid determination of the different BRCA1 alleles, a sequence-specific primer PCR method (PCR-SSP) was established a