Which is the best choice for gastroesophageal disorders:Melatonin or proton pump inhibitors?

• 作 者: Joanna Dulce Favacho de Olivei
• 机 构: UniversidadeFederaldoAmapá,,Laborató,riodeLasereMicroscopiadeForaAt?mica
• 出 处: 世界胃肠药理与治疗学杂志：英文版（电子版）
• 发表日期: 2010年5期
• 关键词: MELATONIN Sleep disorder GASTROESOPHAGEAL REFLUX disease OMEPRAZOLE ULCERS GASTR
• 基金项目: Supported by CNPq (Conselho Nacional de Desenvolvimento Científlico e Tecnológico) (Proc. No. 303358/2009-2)

Melatonin is used in many countries to improve sleep disorders.Melatonin is a hormone produced by the pineal gland and enterochromaff in cells which control sleep and gastrointestinal motility.Low levels of melatonin lead to gastroesophageal reflux diseas