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一些作者观察到慢性丁型肝炎病毒(HDV)感染时存在自身免疫现象。如Crivelli报告在慢性HD患者中13%有抗微粒体膜抗体;Zauli发现50%慢性HD有针对大鼠前胃基底细胞层的抗体(BCLA),78%有对细胞支架成分的抗体;Leukei报告还存在对胸腺星状上皮细胞的抗体(SECA)。本文探讨急性和慢性HD时组织细胞自身抗体的血清学表现。观察对象为急性HD 57例、慢性HD 53例、急性HB 50例、自身免疫性慢性肝炎35例、胆汁性肝硬化25例、结缔组织病24例、健康对照者25名。检查的组织自身抗体有BCLA、SECA、胸腺网状细胞抗体(TRA)和周围胸腺细胞抗体(PTA),后二者尚未见有报道.
Some authors have observed the presence of autoimmunity in chronic hepatitis D virus (HDV) infections. For example, Crivelli reported that 13% of patients with chronic HD had anti-microsomal membrane antibodies; Zauli found 50% of chronic HD with antibodies directed against the anterior gastric basal cell layer of the rat (BCLA) and 78% had antibodies to the scaffolds of the cells; Leukei Report There are also antibodies to thymic stellate cells (SECA). This article explores the serological manifestations of autoantibodies to tissue cells in acute and chronic HD. 57 cases of acute HD, 53 cases of chronic HD, 50 cases of acute HB, 35 cases of autoimmune chronic hepatitis, 25 cases of biliary cirrhosis, 24 cases of connective tissue disease and 25 healthy controls. Tissue autoantibodies tested were BCLA, SECA, TRA and PTA, both of which have not yet been reported.