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用他莫昔芬治疗乳腺癌增加雌激素阴性乳腺癌危险的观点受到专家们的质疑 ,他莫昔芬广泛用于治疗转移性乳腺癌有效已 30年 ,作为辅助治疗和近来用于降低高危妇女乳腺癌的发病率。诊断一侧有乳腺癌的妇女发生对侧肿瘤的危险增加 (2～ 6倍 )。许多研究显示 ,他莫昔芬降低激素受体
The notion that tamoxifen treatment of breast cancer increases the risk of estrogen-negative breast cancer is questionable by experts who have been widely used in the treatment of metastatic breast cancer for 30 years and as adjuvant therapy and more recently for the reduction of women at high risk The incidence of breast cancer. Women diagnosed with breast cancer on one side have an increased risk of contralateral tumors (2 to 6 times). Numerous studies have shown that tamoxifen reduces hormone receptors