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患者女,24岁。平素体健,既往对青霉素过敏。1985年7月18日以“病毒性心肌炎”入院。后因受凉发热给子消炎痛25mg(3次/日)。用药五天患者全身出现散花红色斑丘疹,大小不等搔痒明显,且肝脏开始肿大于右肋下1.5cm,有触疼。双侧腹股沟淋巴结也肿大如花生米〈左1右2〉,质硬活动差,触疼明显查血 WBC12300/mm~3,N40%,L33%,E27%。考虑为消炎痛引起的过敏反应。立即停用消炎痛并静滴地塞米松4mg/日,但皮疹仍持续增多,球结膜及口腔粘膜均被波及,面、背及四肢多处皮疹融合成片,并有溃烂、渗出、结痂。体温也持续上升最高达40.1℃,与此同时肝脾进行性
Female patient, 24 years old. Usually healthy, past allergies to penicillin. July 18, 1985 to “viral myocarditis” admission. After the cold fever to sub-indomethacin 25mg (3 times / day). Five days after treatment, patients with scattered red rash appeared body size ranging from itching obvious, and the liver began to swollen than the right rib 1.5cm, touch pain. Bilateral inguinal lymph nodes also swollen, such as peanuts , poor quality of hard activities, painful touch significantly check blood WBC12300 / mm ~ 3, N40%, L33%, E27%. Consider the allergic reaction caused by indomethacin. Immediate withdrawal of indomethacin and intravenous dexamethasone 4mg / day, but the rash continued to increase, conjunctival and oral mucosa were affected, surface, back and limbs, multiple rash fusion into pieces, and ulceration, exudation, knot scab. Body temperature also continued to rise up to 40.1 ℃, at the same time, liver and spleen progressive