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本文应用普罗帕酮静脉注射治疗小儿各类快速型心律失常32例。显效26例,有效5例,无效1例,总有效率为97%。剂量以单剂3mg/kg疗效最好。静注后即刻显效者84%,最迟者25min,较口服起效快30min至5h。临床显示普罗帕酮静注疗效高,作用迅速,未发现严重副作用。适用于迅速纠正快速型心律失常。对5例患儿测定了有效血药浓度,其范围为93-866ng/ml。
In this paper, propafenone intravenous injection of 32 cases of various types of tachyarrhythmia in children. 26 cases markedly effective, 5 cases effective, 1 case ineffective, the total effective rate was 97%. A single dose of 3mg / kg the best effect. 84% effective immediately after intravenous injection, the latest 25min, faster onset of oral 30min to 5h. Clinical manifestations of propafenone intravenous high efficacy, rapid effect, did not find serious side effects. For rapid correction of tachyarrhythmia. Effective plasma concentrations were measured in 5 children and ranged from 93 to 866 ng / ml.