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目的分析余姚市疑似预防接种异常反应(AEFI)发生情况,评估预防接种服务质量及AEFI监测系统运行质量。方法通过AEFI信息监测系统和月报表收集AEFI病例个案数据,采用描述性流行病学方法对资料进行分析。结果 2011—2015年余姚市共报告AEFI 332例,报告发生率为14.08/10万剂次,白喉破伤风联合疫苗发生率最高,为100.31/10万剂次;一般反应、异常反应和偶合症的报告发生率分别为12.01/10万剂次、1.78/10万剂次和0.30/10万剂次,未出现疫苗质量和接种事故;AEFI病例中,无细胞百白破疫苗引起的AEFI所占比例最高,为41.57%;发生AEFI病例男女性别比为1.91∶1,病例主要发生在<2岁组儿童,占62.65%;夏季(6—8月)报告病例数最多,占36.75%,冬季(12月—次年1月)报告数最少,占13.55%。结论余姚市AEFI监测系统运转正常,应继续提高预防接种人员业务水平,做到及时发现和报告AEFI病例,并给予规范化处置。
Objective To analyze the occurrence of suspected AEFI in Yuyao and evaluate the quality of vaccination services and the operation quality of AEFI monitoring system. Methods The data of AEFI cases were collected through the AEFI information monitoring system and monthly reports. The data were analyzed by descriptive epidemiological method. Results A total of 332 AEFI cases were reported in Yuyao from 2011 to 2015, with a reported incidence of 14.08 per 100 000 doses. The incidence of combined diphtheria tetanus vaccine was 100.31 per 100 000 doses. The general response, abnormal reaction and coupled disease The reported incidence rates were 12.01 / 100,000 doses, 1.78 / 100,000 doses and 0.30 / 100,000 doses respectively. No vaccine quality and vaccination accidents occurred. In AEFI cases, the proportion of AEFI caused by cell-free diphtheria-pertussis vaccine The highest was 41.57%. The male / female sex ratio of AEFI cases was 1.91:1, the cases mainly occurred in children <2 years old, accounting for 62.65%; the highest cases were reported in summer (June-August), accounting for 36.75% Month - next January) The least reported, accounting for 13.55%. Conclusion The AEFI monitoring system in Yuyao City is in normal operation. The business level of vaccination personnel should be continued to be improved so that the cases of AEFI can be found and reported in a timely manner and given standardized treatment.