论文部分内容阅读
目的探析急性心肌梗死(AMI)患者早期诊治中血清心肌钙蛋白T(cTnT)和氨基末端脑钠肽前体(NTproBNP)的临床检测意义。方法分析2013年5月至2015年10月在我院接受治疗的118例高度疑似AMI患者的临床资料。根据临床诊断将入选者分成观察组(AMI患者,62例)和对照组(非AMI患者,56例)两组。比较两组患者的一般资料、cTnT、NT-proBNP水平以及cTnT、NT-proBNP单项及两者联合检测价值。结果两组患者的一般资料组间比较均无统计学差异(P>0.05)。观察组患者的cTnT、NT-proBNP水平明显较对照组高(P<0.01)。cTnT、NT-proBNP单项检测的敏感性(82.3%,83.95%)明显低于联合检测(91.9%),特异性(78.6%,82.1%)也明显较联合检测(92.9%)低(P<0.05)。结论血清cTnT与NT-proBNP的联合检测在AMI患者的早期诊断中发挥了重要作用,具有较高的特异性和敏感性,值得推广。
Objective To investigate the clinical significance of serum cardiac troponin T (cTnT) and amino-terminal pro-brain natriuretic peptide (NTproBNP) in the early diagnosis and treatment of acute myocardial infarction (AMI). Methods Clinical data of 118 highly suspected AMI patients treated in our hospital from May 2013 to October 2015 were analyzed. According to clinical diagnosis, the participants were divided into observation group (AMI patients, 62 cases) and control group (non-AMI patients, 56 cases). General data, cTnT, NT-proBNP levels and the combined detection of cTnT and NT-proBNP were compared between the two groups. Results There was no significant difference in general data between the two groups (P> 0.05). The levels of cTnT and NT-proBNP in the observation group were significantly higher than those in the control group (P <0.01). The sensitivity (82.3%, 83.95%) of single detection of cTnT and NT-proBNP was significantly lower than that of combined detection (91.9%) and specificity (78.6%, 82.1% ). Conclusions The combined detection of serum cTnT and NT-proBNP plays an important role in the early diagnosis of AMI patients, with high specificity and sensitivity and worthy of promotion.