最新过激化疗完成后急性淋巴细胞白血病患儿的免疫缺陷

• 作 者: Brodtman D.H. Rosenthal D.W. Redner A. V.R. Bonagura 李丹
• 机 构: 410 Lakevill e Rd New Hyde Park NY 11042 United States Dr.,
• 出 处: 世界核心医学期刊文摘(儿科学分册)
• 发表日期: 2005年10期
• 关键词: 免疫缺陷 保护性抗体 白喉类毒素 抗原抗体反应 抗体滴度 脊髓灰质炎病毒 流感嗜血杆菌 抗原 体液免疫 抗体

Objective: To determine the prevalence, duration, and a potential cause of hum oral defect(s) in children with acute lymphoblastic leukemia (ALL) at least 1 ye ar after completion of chemotherapy. Study design: Antibody titers for mumps, ru beola, rubella, tetanus and diptheria toxoid, poliovirus serotypes 1, 2,and 3, H aemophilus influenzae type b, varicella, and hepatitis B were obtained from 100 children with ALL. Children with non-protective titers to these microbial antig ens were revaccinated and re-studied after anamnestic vaccine challenge. Result s: The percent of children with ALL wrotection.

Objective: To determine the prevalence, duration, and potential cause of hum oral defect (s) in children with acute lymphoblastic leukemia (ALL) at least 1 ye ar after completion of chemotherapy. Study design: Antibody titers for mumps, ru beola, rubella, tetanus and diptheria toxoid, poliovirus serotypes 1, 2, and 3, H aemophilus influenzae type b, varicella, and hepatitis B were obtained from 100 children with ALL. Children with non-protective titers to these microbial anti-graft were revaccinated and re -studied after anamnestic vaccine challenge. Result s: The percent of children with ALL wrote section.