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目的:探讨非霍奇金淋巴瘤患者医院感染病原体的构成及耐药情况,旨在指导临床合理用药。方法:回顾调查528例住院非霍奇金淋巴瘤患者中发生医院感染的115例患者,对其病原菌进行药敏试验。结果:非霍奇金淋巴瘤患者医院感染发生率较高为21.8/;感染部位以呼吸道为主,病原体以革兰阴性菌为主,占39.0/,革兰阳性菌占37.3/,真菌占23.7/,耐药菌株不断增加。结论:非霍奇金淋巴瘤易发生医院感染,应引起高度重视并积极处理。
Objective: To investigate the composition and drug resistance of nosocomial pathogens in patients with non-Hodgkin’s lymphoma and to guide clinical rational drug use. Methods: A retrospective survey of 528 hospitalized patients with non-Hodgkin’s lymphoma occurred in 115 patients with drug-susceptible tests of their pathogens. Results: The incidence of nosocomial infection was 21.8% in non-Hodgkin’s lymphoma patients. The main respiratory tract was respiratory tract. Gram-negative bacteria were the main pathogens, accounting for 39.0%, Gram-positive bacteria accounting for 37.3% and fungi accounting for 23.7% /, Drug-resistant strains continue to increase. Conclusion: Non-Hodgkin’s lymphoma is prone to nosocomial infection, which should be paid great attention and actively treated.