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目的探讨泮托拉唑治疗消化性溃疡合并出血的临床效果。方法 100例消化性溃疡合并出血患者,随机分为观察组和对照组,各50例。两组均给予常规治疗,对照组患者给予奥美拉唑治疗,观察组患者给予泮托拉唑治疗。评定两组治疗效果,观察不良反应发生情况。结果观察组治疗后的临床效果总有效率为96.0%,对照组治疗后的总有效率为78.0%,观察组总有效率高于对照组,差异有统计学意义(P<0.05)。观察组不良反应发生率(8.0%)低于对照组(32.0%),差异有统计学意义(P<0.05)。结论泮托拉唑治疗消化性溃疡合并出血疗效显著,用药安全,值得借鉴。
Objective To investigate the clinical effect of pantoprazole in the treatment of peptic ulcer with hemorrhage. Methods 100 cases of patients with peptic ulcer bleeding, were randomly divided into observation group and control group, 50 cases each. Both groups were given routine treatment, the control group were given omeprazole treatment, the observation group was given pantoprazole treatment. The curative effect of two groups was evaluated and the incidence of adverse reactions was observed. Results The total effective rate of the observation group after treatment was 96.0%. The total effective rate of the control group after treatment was 78.0%. The total effective rate of the observation group was higher than that of the control group (P <0.05). The incidence of adverse reactions in the observation group (8.0%) was lower than that in the control group (32.0%), the difference was statistically significant (P <0.05). Conclusion Pantoprazole treatment of peptic ulcer bleeding with significant effect, drug safety, it is worth learning.