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对北京市近年发生的疫苗相关的麻痹型脊髓灰质炎（VAPP）病例进行了综合描述与分析。结果显示：VAPP主要为接受第1剂口服脊髓灰质炎疫苗（OPV）后的2～3月龄男婴，其临床症状典型，少数患儿可完全恢复；本市近年未发现接触服苗的间接相关病例。本文提示：我市服菌病例主要与Ⅲ型疫苗病毒有关；且VAPP在第1剂服苗儿童中的危险性高达13．3／100万，高于美国和世界卫生组织报道。本文系国内首次报道VAPP免疫功能检测资料，对探明VAPP发病原因可能具有重要的意义．
A comprehensive description and analysis of the vaccine-associated paralytic poliomyelitis (VAPP) that occurred in Beijing in recent years were carried out. The results showed that VAPP was mainly for 2 to 3 month-old male infants who received the first dose of oral polio vaccine (OPV). The clinical symptoms were typical and a small number of children were completely recovered. There was no indirect contact with the vaccine Related cases. This article suggests that the prevalence of serotype III vaccine in our city is mainly related to type III vaccine virus. The risk of VAPP in the first dose of vaccine-bearing children is as high as 13.3 / 1 million, higher than that reported by the United States and the World Health Organization. This article is the first report of VAPP immune function test data in China, to explore the pathogenesis of VAPP may have important significance.