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球红霉素是我国自己筛选、研制、国外还没有的新抗真菌抗菌素,临床应用表明,对念珠菌、隐球菌有较强的抑杀作用,对孢子丝菌、曲菌等也有一定的作用,且副作用较两性霉素B还轻。同种异体肾移植术后,由于使用大量激素、硫唑嘌呤及广谱抗菌素,容易并发真菌感染,治疗困难。我院于1977年对1例肾移植术后并发肺部白色念珠菌及绿脓杆菌感染的患者,经用球红霉素及羧苄青霉素治疗,疗效显著,故报道如下,以供参考。
Erythromycin is our own screening, research and development, there is no new foreign anti-fungal antibiotics, clinical application shows that Candida, Cryptococcus has a strong inhibitory effect on spores, aspergillus also have a role , And side effects than amphotericin B is also light. After allograft renal transplantation, due to the use of a large number of hormones, azathioprine and broad-spectrum antibiotics, fungal infections easily complicated by treatment. Our hospital in 1977 on a case of renal transplant patients with pulmonary Candida albicans and Pseudomonas aeruginosa infection, the use of globulin and carbenicillin treatment, the effect is significant, it is reported below, for reference.