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尼卡地平盐酸盐是二氢吡啶类新型钙通道阻滞剂。其作用与硝苯吡啶相似,为一强效钙拮抗剂,能松弛血管平滑肌,产生明显的血管扩张作用。尼卡地平的降压作用迅速,对脑血管也有扩张作用。日本和西班牙已批准用于脑血管功能不足,美国和欧洲已批准用于心绞痛和高血压。临床研究表明,病人对本品的耐受性很好。我国也已研制成功。国外制造厂商:Syntex(UK);Yama-nouchi(Jap) [化学名称] (±)2.6-Dimethyl-5-methoxycar-bonyl-3-(2-N-benzyl-methylamino)ethoxycarbonyl-4-(3-nitrophenyl)-1.4-dihydrophridine hydrochloride [其它名称] RS-69216; RS-69216-X-X-07-0; YC-93 [合成方法] (1)Iwanami M,et al.Japan Ko-
Nicardipine hydrochloride is a dihydropyridine novel calcium channel blocker. Its role and nifedipine similar to a potent calcium antagonist, can relax vascular smooth muscle, resulting in significant vasodilatation. The antihypertensive effect of nicardipine rapid, also has expansion of cerebral blood vessels. Japan and Spain have been approved for cerebrovascular insufficiency and the United States and Europe have approved for angina and hypertension. Clinical studies have shown that patients tolerate the product well. China has also successfully developed. Foreign manufacturers: Syntex (UK); Yama-nouchi (Jap) [Chemical Name] nitrophenyl) -1.4-dihydrophridine hydrochloride (Other names) RS-69216; RS-69216-XX-07-0; YC-93 [Synthesis Method] (1) Iwanami M, et al.