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糖尿病痛性神经病变以下肢疼痛多见，外擦山莨菪碱乳膏治疗糖尿病性痛肢，临床疗效较好，应用彩色多普勒对２０例接受该治疗的患者痛肢的局部血流动力学有关指标进行动态观察。结果：外擦山莨菪碱乳膏后，痛肢局部血流速度增快，血流阻抗指数下降，血管内径增宽，经统计学处理Ｐ＜００１，差异具有高度显著性意义。认为外擦山莨菪碱乳膏能使局部血液循环改善，并可能通过增加神经的血液供应，改善局部代谢而使糖尿病性肢痛症状缓解。
Diabetic pain neuropathy with lower extremity pain more common, external scrub cream of anisodamine treatment of diabetic painful limbs, clinical efficacy is good, the application of color Doppler in 20 patients receiving the treatment of pain in patients with local hemodynamics The indicators for dynamic observation. Results: After the external scrub cream was applied, the local blood flow velocity of the painful limbs increased rapidly, the index of the blood flow impedance decreased and the diameter of the blood vessels widened. After the statistical treatment P <001, the difference was highly significant. That the external scrub cream anopheline local blood circulation can improve, and may by increasing the blood supply to the nerves, to improve the local metabolism and alleviate the symptoms of diabetic limb pain.