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过去有关柴胡桂枝汤的实验证明,其汤液浸膏对软体动物的神经细胞可产生抗PTZ(戊四唑)的作用,并对小白鼠的听原性系统所发生的痉挛有抑制作用。临床上常用柴胡桂枝汤为抗癫痫药,亦有类似效果。本实验的目的,是为了说明本方剂浸膏,以及本方单味药的各种浸膏,对青蛙的坐骨神经有麻醉作用。本方剂的浸膏以及构成本方中的柴胡、桂枝、生姜对神经纤维亦有麻醉作用。
Past experiments on Chaihu Guizhi Decoction have demonstrated that its decoction extract can produce anti-PTZ (pentylenetetrazolium) activity on the nerve cells of molluscs and inhibit the caries generated in the auditory system of mice. Chaihu Guizhi Decoction is commonly used as an anti-epileptic drug in clinical practice and has similar effects. The purpose of this experiment is to illustrate the extract of this formula, as well as the various extracts of this party’s single herb, and have anesthetic effect on the sciatic nerve of the frog. The extracts of this prescription and Bupleurum, Guizhi, and Ginger, which are included in this prescription, also have anesthetic effects on nerve fibers.