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[目的]观察抗瘤增效方联合西医治疗晚期肺腺癌疗效。[方法]使用随机平行对照方法,将60例住院患者按抽签法随机分为两组。对照组30例①化疗治疗。②西药治疗:吉西他滨,1.2~1.4g/次,1次/第1、8d,静注。顺铂,30mg/次,1次/第1~4d,静注。(或长春瑞滨,40mg/次,1次/第1、8d,口服。顺铂,30mg/次,1次/第1~4d,静注。)治疗组30例抗瘤增效方(黄芪、太子参各30g,苍白术10g,茯苓18g,黄精、补骨脂各12g,半枝莲60g,甘草9g),1剂/d,水煎300mL,早晚口服。西医治疗同对照组。连续治疗28d为1疗程。观测临床症状、生存期、不良反应。连续治疗2疗程,判定疗效。[结果]治疗组明显改善12例,部分改善6例,无改善7例,恶化5例,总有效率83.33%。对照组明显改善4例,部分改善3例,无改善7例,恶化16例,总有效率46.67%。治疗组疗效优于对照组(P<0.05)。生存期治疗组优于对照组(P<0.05)。[结论]抗瘤增效方联合西医治疗晚期肺腺癌效果显著,值得推广。
[Objective] To observe the curative effect of anti-tumor and side-effect prescription combined with western medicine on advanced lung adenocarcinoma. [Methods] Randomized parallel method was used to divide 60 hospitalized patients into two groups according to random selection. Control group of 30 patients with chemotherapy. Western medicine treatment: Gemcitabine, 1.2 ~ 1.4g / time, 1 / first, 1,8d, intravenous injection. Cisplatin, 30mg / time, 1 times / 1 ~ 4d, intravenous injection. (Or vinorelbine, 40mg / time, 1 / first and 1,8d, oral cisplatin, 30mg / time, 1 times / 1 ~ 4d, intravenous injection.) Treatment group, 30 cases of anti-tumor efficacy formula , Heterophylla 30g, pale surgery 10g, Poria 18g, Polygonatum, psoralen the 12g, Scutellaria barbata 60g, licorice 9g), 1 / d, decoction 300mL, morning and evening oral. Western medicine treatment with the control group. Continuous treatment 28d for a course of treatment. Observation of clinical symptoms, survival, adverse reactions. Continuous treatment of 2 courses to determine the efficacy. [Results] The treatment group improved significantly in 12 cases, partial improvement in 6 cases, no improvement in 7 cases, worsening in 5 cases, the total effective rate was 83.33%. Control group improved significantly in 4 cases, partial improvement in 3 cases, no improvement in 7 cases, 16 cases of deterioration, the total efficiency of 46.67%. The treatment group was better than the control group (P <0.05). Survival of the treatment group was better than the control group (P <0.05). [Conclusion] The anti-tumor and side-effect prescription combined with western medicine has significant effect on advanced lung adenocarcinoma and is worth promoting.