论文部分内容阅读
目的了解墨脱县1262名中小学生乙型肝炎病毒(HBV)感染状况,为乙肝防治工作的开展提供依据。方法用酶联免疫方法检测HBsAg、抗-HBs、HBeAg、抗-HBe和抗-HBc五项乙肝标志物,Excel统计软件对检测结果进行统计分析。结果1262名中小学生乙肝标志物五项全阴者有886人,占70.2%;仅有303名中小学生有保护性的乙肝表面抗体,占24.0%;39名学生HBsAg阳性,阳性率3.1%。HBsAg阳性39名学生中,HBsAg、HBeAg和抗-HBc三项阳性的学生有27名,占69.2%。结论1262名中小学生中乙肝标志物五项全阴者比例较高,有保护性抗体的比例较低,存在接触感染乙肝病毒的较大风险,因此,加强西藏墨脱县中小学生乙肝疫苗接种工作刻不容缓。
Objective To understand the status of hepatitis B virus (HBV) infection among 1262 primary and secondary school students in Medog County, and provide a basis for the prevention and treatment of hepatitis B infection. Methods Five markers of HBsAg, anti-HBs, HBeAg, anti-HBe and anti-HBc were detected by enzyme-linked immunosorbent assay (ELISA), and statistical analysis was performed by Excel statistical software. Results There were 886 persons (accounting for 70.2%) of all the 6262 primary and secondary school students with hepatitis B markers. Only 303 primary and secondary school students had protective hepatitis B surface antibody (24.0%). The positive rate of HBsAg in 39 students was 3.1%. Of the 39 HBsAg positive students, 27 were HBsAg, HBeAg and anti-HBc positive, accounting for 69.2%. Conclusions There is a high proportion of 1262 primary and middle school students who have hepatitis B markers, and the proportion of protective antibodies is relatively low, which exposes them to a greater risk of exposure to hepatitis B virus. Therefore, hepatitis B vaccination among primary and secondary students in Medog County, Tibet Autonomous Region No delay.