A New Hybrid Model of Amino Acid Substitution for Protein Functional Classification

• 作 者: Ke Long WANG Zhi Ning WEN Fu S
• 机 构: College of Chemistry,State Key Laboratory of Chemo/Biosensing and Chemometrics
• 出 处: 中国化学快报（英文版）
• 发表日期: 2004年期
• 关键词: Hybrid model of amino acid substitution protein functional classification Fisher

In this paper, a new hybrid model of amino acid substitution is developed and compared with the others in previous works. The results show that the new hybrid model can characterize the protein sequences very well by calculating Fisher weights, which can denote how much the variants contribute to the classification.