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恶性滋养细胞肿瘤(恶性葡萄胎及绒癌)是妇科恶性肿瘤之一,往往通过血道迅速转移,广泛扩散到全身各器官。过去对此病治疗多采用手术及放射治疗,但效果均不满意,国内、外报告死亡率均很高,对妇女生命威胁甚大。我国首都医院应用大剂量化学药物治疗后,绒癌死亡率从1958年的89.2%下降至1975年21.4%,恶葡死亡率从25.9%逐步下降到接近于零。我院自1951～1977年,27年来恶葡死亡14例,绒癌70例(包括恶葡复发8例),共84例。兹将其死亡有关资料作一分析,为今后对此病的诊断、治疗提供参考,从而减少死亡率,提高治愈率。
Malignant trophoblastic tumor (malignant mole and choriocarcinoma) is one of gynecological malignancies, often rapidly transferred through the bloodstream, widely spread to all parts of the body. In the past, the use of surgery and radiotherapy for the treatment of this disease was more, but the results were unsatisfactory. Both domestic and overseas reported high mortality rates and threatened the lives of women. The mortality rate of choriocarcinoma dropped from 89.2% in 1958 to 21.4% in 1975 in the Capital Hospital of China after the application of high-dose chemical therapy. The mortality rate of euthanasia gradually decreased from 25.9% to nearly zero. In our hospital from 1951 to 1977, 27 cases of calamity death in 14 cases, 70 cases of choriocarcinoma (including the recurrence of malignant pterygium in 8 cases), a total of 84 cases. It will be an analysis of the death of the relevant information for future diagnosis and treatment of the disease provide a reference to reduce mortality and improve the cure rate.