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目的探讨系统性红斑狼疮并发肺孢子虫肺炎(PCP)的诊断和防治措施。方法研究1例系统性红斑狼疮并发肺孢子虫肺炎患者的临床表现、实验室检查结果、影像学资料以及诊断和治疗的方法。结果患者出现发热、干咳、无痰、胸闷、伴阵发性呼吸困难等症状,血氧饱和度下降,胸部CT显示两肺部毛玻璃状改变,肺泡灌洗液找到肺孢子虫。给予复方新诺明、卡泊芬净、调整免疫抑制剂及其它支持对症治疗,痊愈出院。结论免疫功能抑制患者有发热、干咳、呼吸困难等临床症状,应考虑PCP并及时做病原学检查。
Objective To investigate the diagnosis and control of systemic lupus erythematosus complicated with pneumococcal pneumonia (PCP). Methods A case of systemic lupus erythematosus complicated with pneumococcal pneumonia in patients with clinical manifestations, laboratory tests, imaging data and diagnosis and treatment methods. Results The patients showed symptoms of fever, dry cough, no sputum, chest tightness and paroxysmal dyspnea, decreased oxygen saturation, chest CT showed gross glassy changes in both lungs and pneumocystis lavage. Given compound cotrimoxazole, caspofungin, adjust immunosuppressive agents and other support symptomatic treatment, discharged. Conclusions Patients with immune dysfunction may have clinical symptoms such as fever, dry cough and dyspnea. PCP should be considered and etiological examination should be done in time.