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目的 :探讨强化降脂联合强化降压预防脑卒中患者不良事件方面的临床价值。方法 :将我院收治的190例脑卒中患者随机分为观察组和对照组,观察组的采用强化降脂联合强化降压治疗,对照组采用常规降脂联合常规降压治疗,治疗12个月后,比较两组患者血脂、血压水平及不良事件发生情况。结果 :观察组的舒张压、收缩压、LDL-C水平明显低于对照组,不良事件的主要终点事件和次要终点事件的发生率显著低于对照组。结论 :强化降脂联合强化降压有助于改善脑卒中患者的血压和血脂,还可有效预防心血管不良事件的发生,故可将其作为治疗脑卒中的优先考虑方案。
Objective: To investigate the clinical value of enhancing lipid-lowering combined with antihypertensive effect in the prevention of adverse events in stroke patients. Methods: A total of 190 stroke patients admitted to our hospital were randomly divided into observation group and control group. The observation group was treated with intensive lipid-lowering and intensive antihypertensive treatment. The control group was treated with conventional lipid-lowering therapy combined with conventional antihypertensive treatment for 12 months After comparing the two groups of patients with blood lipids, blood pressure levels and adverse events. Results: The diastolic blood pressure, systolic blood pressure and LDL-C level in the observation group were significantly lower than those in the control group. The incidence of the primary end point and secondary end point of the adverse events was significantly lower than that of the control group. CONCLUSION: Intensive lipid-lowering therapy combined with intensive antihypertensive therapy can help to improve blood pressure and blood lipids in stroke patients, and can effectively prevent the occurrence of cardiovascular adverse events. Therefore, it can be regarded as a priority for the treatment of stroke.