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一般认为,输血引起的免疫抑制作用对恶性肿瘤病人的治疗可能是不利的。Burrows对122例结、直肠腺癌术后的回顾性调查显示,曾接受输血的患者生存率及健在率均低于未接受输血者,复发率则高于后者。即使术后作化疗或免疫治疗,这种差异仍有统计学意义。Foster对性别、年龄、病期、组织学分类及病灶部位作调整后,二者问差异仍有意义。Hyman对肺癌切除术病例回顾性分析也有类似结果。
It is generally believed that the immunosuppression caused by blood transfusions may be detrimental to the treatment of patients with malignant tumors. Burrows’s retrospective investigation of 122 patients with colorectal adenocarcinoma showed that the survival rate and survival rate of patients who had received blood transfusion were lower than those who did not receive blood transfusion, and the recurrence rate was higher than the latter. Even after chemotherapy or immunotherapy, this difference was still statistically significant. After Foster’s adjustment of gender, age, stage of disease, histological classification, and lesion location, the difference between the two remained significant. Hyman’s retrospective analysis of lung cancer resection has similar results.