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1973年Bishop报告了病毒与腹泻关系的电镜资料,这种病毒就是轮状病毒。人类轮状病毒(HRV)呈球形,直径70nm,有双壳结构,电镜下显示宽毂,短辐及轮的薄边,其双倍染色体组是11段,并含有RNA聚合酶。能耐56℃、pH3及许多净化剂及溶剂。HRV起码有二,还可能有四个血清型。来自全世界的流行病学调查表明:全年小儿腹泻住院病例大约一半有由HRV引起,夏季腹泻有0-20%而冬季腹泻70—80%与HRV有关,可能在较暖的地方一年到头均可成为病原。主要感染6个月到二岁的小儿,
Bishop in 1973 reported the relationship between viruses and diarrhea by electron microscopy, the virus is rotavirus. Human rotavirus (HRV) has a spherical shape with a diameter of 70 nm and has a bivalve structure. The electron microscopy shows a wide hub, a short hub and a thin rim of a wheel. The double chromosomal group is 11-segment and contains RNA polymerase. Capable of 56 ℃, pH3 and many purification agents and solvents. HRV at least two, but also may have four serotypes. Epidemiological surveys from around the world indicate that about half of all hospitalizations for pediatric diarrhea throughout the year are caused by HRV, with 0-20% in summer diarrhea and 70-80% in winter diarrhea associated with HRV, possibly in warmer places throughout the year Become a pathogen. The main infection in 6 months to two-year-old children,