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支气管哮喘 (以下简称哮喘 )的基本特征是气道炎症、微血管渗漏、粘液分泌增加、平滑肌收缩所致的可逆性气道阻塞及支气管高反应性 (BHR)。大量资料表明哮喘患者其血栓素 A2 (TXA2 )及相关前列腺素如前列腺素 D2 、前列环素 (PGI2 )的生成量均高于正常人 ,这些物质能诱发上述哮
Bronchial asthma (hereinafter referred to as asthma) is characterized by airway inflammation, microvascular leakage, increased mucus secretion, reversible airway obstruction caused by smooth muscle contraction and bronchial hyperresponsiveness (BHR). A large number of data show that patients with asthma thromboxane A2 (TXA2) and related prostaglandins such as prostaglandin D2, prostacyclin (PGI2) generation were higher than normal, these substances can induce the above asthmatic