Quantification of Erdosteine in the Low-volume of Dog Plasma by Liquid Chromatography Tandem Mass Sp

• 作 者: LIU Dan WANG Yan TANG Yun-biao
• 机 构: Laboratory of Drug Metabolism and Pharmacokinetics,The First Hospital of Jilin University,Department
• 出 处: 高等学校化学研究（英文版）
• 发表日期: 2004年期
• 关键词: Erdosteine Dog plasma Pharmacokinetics HPLC/MS/MS

IntroductionErdosteine[N-(carboxymethylthioacetyl )-homocysteine thiolactone](Fig. 1) is a synthetic derivative of natural amino acid methionine[1].