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丝虫病的治疗,海群生是主要的药物,到目前为止,还没有在疗效方面超过它的药物出现。国内学者也证实海群生能使血内微丝蚴迅速消失,或大量减少(1—5)。1954年陈氏等治疗丝虫病2,096例(2),从淋巴结节的出现和解剖结节的结果,肯定了海群生也能使班氏和马来丝虫的成虫死亡。1955年刘氏等的报告中也有3例在精索和付睪部病理切片中显示新近发生的嗜伊红性脓肿(5).这种效果尤以应用大剂量短程者更为显著,所以近来逐渐趋向于增大剂量和缩短日程,治程从2—3周逐渐缩短到七天、三天、二天乃至一天;剂量也从每次50—100毫克增加到200—500毫克,甚至更大(7).
Treatment of filariasis, sea qun is the main drug, so far, there is no more than its efficacy in the emergence of drugs. Domestic scholars also confirmed that sea-based microfilaria can quickly disappear within the blood, or a substantial reduction (1-5). In 1954, 2,096 cases of filariasis were treated by Chen et al. (2). From the appearance of lymphatic nodes and the results of anatomical nodules, it was confirmed that the sea quizheng could also kill adult worms and banded insects. In the case of Liu et al. In 1955, three new cases of eosinophilic abscess were also shown in the spermatic cord and in the biopsy section (5). This effect is particularly evident with the use of large doses and short courses, so recently Gradually tend to increase the dose and shorten the schedule, the course of treatment gradually reduced from 2-3 weeks to seven days, three days, two days or even a day; dosage from 50-100 mg per dose to 200-500 mg or more (7 ).