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二、氨基糖苷类氨基糖苷类抗生素包括庆大霉素、丁胺卡那霉素(本品对乙酰转移酶、磷酸转移酶、核苷转移酶等多种氨基糖苷类钝化酶稳定)、妥布霉素、奈替米星等。对G~+(主要是金葡球菌)及G~-菌均有效,具有1～3小时或更长的抗生素后续作用。目前国内外多数学者认为氨基糖苷类抗生素以每日给药一次为宜,在每日用量不变的情况下,单次给药后药物的抗菌活性、疗效及毒性反应均优于多次给药,且不易产生耐药株,与β内酰胺
Second, aminoglycosides aminoglycoside antibiotics, including gentamicin, amikacin (the goods on the acetyltransferase, phosphotransferase, nucleoside transferase and other aminoglycoside enzyme inactivation), Tobramycin, netilmicin and others. For G ~ + (mainly Staphylococcus aureus) and G ~ - are effective, with 1 to 3 hours or longer follow-up of antibiotics. At present, most scholars at home and abroad think that aminoglycoside antibiotics should be administered once a day. Under the same daily dosage, the antibacterial activity, curative effect and toxicity of the drug after single administration are better than multiple administration , And not easy to produce resistant strains, and β-lactam