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本文对具有消化道症状558例2个月～13岁小儿进行胃镜检查与病理活检,检出幽门螺杆菌(HP)192例,检出率34.4％,其中男124例,女68例,分6个年龄组。结果表明:(1)小儿HP感染率随年龄增长而上升,6岁以上发病机会逐年增高;(2)临床表现主要以腹痛、呕吐、消化道出血及厌食等症状,急性发病占1/4;(3)组织学改变以粘膜固有层内慢性炎症与淋巴滤泡形成为特征。胃镜下粘膜“微小结节”改变中约50％有可能HP感染,其与淋巴滤泡有良好的相关性;(4)小儿HP感染与GU关系不如成人显著,与DU的关系与成人相似。
In this paper, 558 patients with gastrointestinal symptoms from 2 months to 13 years old children underwent gastroscopy and biopsy, 192 cases of Helicobacter pylori (HP) were detected, the detection rate was 34.4%, including 124 males and 68 females, Age group The results showed that: (1) The prevalence of HP infection in children increased with age, and the chances of getting over 6 years of age increased year by year; (2) The clinical manifestations mainly included abdominal pain, vomiting, gastrointestinal bleeding and anorexia, (3) histological changes in the lamina propria of chronic inflammation and lymphoid follicles characterized. Gastroscopy “tiny nodules” changes in about 50% of possible HP infection, and lymphoid follicles have a good correlation; (4) Children with HP infection and GU is not as significant as adults, and DU and the relationship between adults and similar.